• Clinical trials,  Drug development,  Medicine,  Medicine & Politics,  Public health

    Coronavirus Tidbits # 23-3-29 20

    Quick links News     Diagnostics     Drugs     Epidemiology/Infection control     Tips     Politics    Feel good du jour     Comic relief     Perspective/Poem     Bits of beauty Coronavirus Tidbits #    News  Fauci predicts millions of coronavirus cases in US, and more than 100,000 deaths Trump now agrees to extend the social distancing recommendation until the end of April, after recently saying he wanted the country “opened up and raring to go” by Easter" ~ ~ ~ This morning's WTH? Pay cuts and withholding back pay for some doctors and nurses as they battle on the front line of #COVID19 https://www.bostonglobe.com/2020/03/27/metro/coronavirus-rages-doctors-hit-with-cuts-compensation/?event=event25 via @BostonGlobe ~…

  • Clinical trials,  Medicine,  Medicine & Politics,  Public health,  Uncategorized

    Coronavirus Tidbits # 21 3-28-20

    News:  Best news of the day: ‘Going full-on MacGyver’ – U of MN doctor creates makeshift ventilators to battle COVID-19 Even better, in some ways, he’s also made the plans OPEN Source and will be updating here Physical Prototype Video: https://youtu.be/3ssVoWEVxw4 CAD Prototype Video: https://youtu.be/RpEqtGa2vTI Diagnostics: Rapid diagnostic tests are winning approval, like this 5-minute coronavirus test by Abbott Laboratories that won emergency FDA approval The problem is that we don’t yet know enough about the accuracy of the tests, known as sensitivity and specificity? In particular, is a negative test really negative. Until we know more, many ID experts recommend assuming someone who has symptoms is infectious, even if the test is…

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  • Infectious disease,  Medicine,  Medicine & Politics,  Public health,  Uncategorized

    Coronavirus Tidbits #20 3-27-20  

    News  Wondering if you should seek care for suspected COVID-19? Apple and CDC have a new app and symptom checker with a decision tool. https://www.apple.com/covid19 When can we stop the social distancing? We can’t…at least until there is widespread testing. Then you could monitor and slowly loosen restrictions in selected areas. “To consider letting off on social distancing will require sharp decline in cases, widely available rapid diagnostics wherever pts get clinical care, the right PPE available to all HCWS who need it, safe and good hospital capacity to deal with all pts with COVID.” Tom Inglesby, Johns Hopkins Here’s a thread by Scott Gottlieb that explains more: Our path…

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  • Clinical trials,  Drug development,  Medicine,  Medicine & Politics,  Public health

    Coronavirus Tidbits # 19 3-26-20

    News: This is very exciting to me and the best news of the day. I met David Fajgenbaum at a conference to launch CURE ID, the Drug Repurposing program I’ve been excited about. Go watch this video, starting at ~3:42:14 of his remarkable story. He’s translated that drive into #COVID19 research now and his team has done remarkable work extracting data in just 6 days! Also go watch ~31:40” for a 10 minute talk from Shira Strongin (I’ve written about her and rare diseases before) on her life before and after a repurposed Hail Mary drug for her rare disease. I’ve been excited about drug repurposing for years for its potential to…

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  • Infectious disease,  Medicine,  Medicine & Politics,  Public health

    Coronavirus tidbits # 18 3-25-20

    News: One doctor’s straight talk about the coronavirus strikes a chord with anxious Americans This is an excellent, very short clip. Highly recommended Emily Landon https://www.washingtonpost.com/health/2020/03/20/emily-landon-coronavirus/ Perspective: The coronavirus economic downfall will affect those who can least afford it https://www.zmescience.com/science/the-coronavirus-economic-downfall-will-affect-those-who-can-least-afford-it/ Why you should stay at home: My friend Shira is a superstar with her advocacy for patients with #RareDiseases, and is the founder of Sick Chicks. She posted this selfie partying with her parents. They have a remarkable sense of humor, generosity, and resilience. Let’s keep them and all the #vulnerable folks in our lives safe.   Diagnostics: Companies, countries, buying robots to increase testing https://www.zmescience.com/science/spain-coronavirus-robots-92253552/ Drugs: Another chapter in why…

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  • Infectious disease,  Medicine,  Medicine & Politics,  Public health

    Coronavirus Tidbits #13 3/19/20

    My new post @Forbes: An Unexpected Loss Of Smell And Taste In Coronavirus Patients https://www.forbes.com/sites/judystone/2020/03/20/theres-an-unexpected-loss-of-smell-and-taste-in-coronavirus-patients/#4a59103f5101 Epidemiology: From Stanford ER: Of the 562 patients, 127 (22.6%) were positive for other viruses. (24.5% if we use 181+336 = 517 as denominator). Of the 49 positive SARS-COV-2 results, 11 (22.4%) also had a co-infection. Of the 127 positive for other viruses, 11 (8.66%) had a SARS-COV-2 co-infection. These co-infection rate are much higher than previously reported rates. Good explainer on incubation and infectious periods by Ian Mackay, Australian virologist https://virologydownunder.com/politically-infectious-period/ Coronavirus is running so rampant in Colorado’s mountains residents, visitors should “minimize all contact with other people” https://coloradosun.com/2020/03/15/coronavirus-colorado-mountains/ Our health department reports no…

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