
Coronavirus & Monkeypox Tidbits #215 10/16/22
Announcements:
First, there is now a Resources Page here for the most commonly asked questions I'm getting.
Happy to continue to answer your questions/concerns as best I can, so don't be shy about that.
New Post:
CDC's New Mask Guideline Says Vulnerable People Are Expendable
News
Covid:
Study: Long-COVID symptoms burdened 29% of survivors
A German study published today in BMJ finds a considerable burden of long-COVID symptoms, especially fatigue and neurocognitive impairment ("brain fog"), at 6 to 12 months—even among young and middle-aged adults who had mild infections.
A team led by Ulm University researchers parsed responses to a mailed survey from 11,710 adults aged 18 to 65 years living in southwestern Germany who tested positive for COVID-19 from Oct 1, 2020, to Apr 1, 2021, a period dominated by the wild-type virus.
Average participant age was 44.1 years, 58.8% were women, 56.8% were employed full-time before the pandemic, 77.5% didn't require medical care for their infection, 19.0% needed outpatient care, and less than 4% were hospitalized. Pre-existing chronic conditions included musculoskeletal disorders (28.9%), cardiovascular disease (17.4%), neurologic and sensory disorders (16.2%), and respiratory illnesses (12.1%).
The survey was fielded in August and September 2021, and the average interval between the initial positive COVID-19 test and survey completion was 8.5 months.
Most at risk: Women, those who needed medical care
The researchers sorted 30 new-onset long-COVID symptoms into 13 clusters. Respondents reported fatigue (37.2%) and brain fog (31.3%), a symptom cluster that the researchers said contributed most to reduced health recovery and working capacity. Other symptoms contributing to reduced work capacity included chest symptoms (30.2%), impaired taste or smell (23.6%), and anxiety and depression (21.1%).
Assuming at least moderate impairment in activities of daily living and 80% or less recovery of general health or working capacity, the estimated rate of long-COVID was 28.5% among participants (extrapolated to 8.4% for all women and 4.6% for all men in the community, if all nonrespondents had recovered completely).
Women reported more impairment than men for most new symptoms.
https://www.cidrap.umn.edu/news-perspective/2022/10/study-long-covid-symptoms-burdened-29-survivors
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U.S. FDA Considers Another COVID-19 Antiviral
Veru Inc. today announced that positive data from the Phase 3 trial of sabizabulin for hospitalized moderate to severe COVID-19 patients who required supplemental oxygen has been accepted as a late-breaker oral presentation on October 19-23, 2022, in Washington, D.C.
Treatment with sabizabulin 9 mg once daily, an oral, first-in-class, new chemical entity, microtubule disruptor with dual anti-inflammatory and antiviral properties, resulted in a clinically meaningful and statistically significant 55.2% relative reduction in deaths compared to placebo.
Based on a planned interim analysis of the first 150 randomized patients, the Independent Data Monitoring Committee unanimously halted the study for clear clinical efficacy, and no safety concerns were identified.
Additionally, the U.S. FDA has informed the Company that FDA’s Pulmonary-Allergy Drugs Advisory Committee will meet on November 09, 2022, to discuss the Company’s sabizabulin for COVID-19 request for emergency use authorization.
Sabizabulin is an orally bioavailable bis-indole that binds to the “colchicine binding site” of alpha and beta tubulin and inhibits tubulin polymerization at low nanomolar concentrations.
Sabizabulin disrupts the microtubules, the central mechanism contributing to their antiviral and anti-inflammatory activities.
Drugs like sabizabulin that target microtubules have broad antiviral activity by disrupting the intracellular transport of viruses such as SARS CoV-2,
https://www.precisionvaccinations.com/2022/10/13/us-fda-considers-another-covid-19-antiviral
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Study finds >40% mislead others about their use of Covid precautions
~ ~ ~
“Combined, the two new strains make up the largest proportion of infections in the New York and New Jersey region. Around 20% of infections there are already from BQ.1 or BQ.1.1, CDC estimates.” Level 5 and 6 variants now total about 10% of U.S. infections https://t.co/AlkT7jZsIC
— Scott Gottlieb, MD (@ScottGottliebMD) October 14, 2022
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So much for the pandemic being over:
Biden administration extends COVID public health emergency https://t.co/im0hN6bQuj via @medical_xpress
— Judy Stone (@DrJudyStone) October 15, 2022
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Positivity rate of 27% according to the Walgreens testing. Absolute catastrophe in the U.S. right now — willful negligence and normalization of death and disability by our policymakers. pic.twitter.com/XwGWWWcQIB
— Joaquín Beltrán for Downey (@joaquinlife) October 7, 2022
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"We have plenty still to understand about long COVID, particularly in the vaccinated population, but Al-Aly estimates that 8% to 12% of vaccinated people with breakthrough infections may die due to long COVID.
— Yaneer Bar-Yam (@yaneerbaryam) October 8, 2022
2/
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Monkeypox:
US hits 27,000 monkeypox cases as Siga tests Tpoxx in clinical trials
The CDC updated its case count yesterday, and the United States has 244 more monkeypox cases, raising the national total to 27,022.
The European Centre for Disease Prevention and Control (ECDC), meanshile said 24,973 cases have been identified in that region since spring, when the largest global outbreak of the virus was first detected in the United Kingdom.
Currently in the United States, United Kingdom, and the Democratic Republic of the Congo (DRC), drugmaker Siga is conducting clinical trials on its antiviral Tpoxx, which is being used to shorten the duration of the virus in patients around the world under emergency use authorizations. The trials will assess the safety and efficacy of the drug in monkeypox patients; investigators aim to enroll 500 participants each at US and UK sites and 450 participants in the DRC.
Oct 12 CDC report
Oct 12 ECDC report
Oct 12 Siga press release
Oct 12 Exp Dermatol study
https://www.cidrap.umn.edu/news-perspective/2022/10/news-scan-oct-13-2022
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New study finds that monkeypox virus can spread widely within specialist hospital isolation rooms
Monkeypox virus can be shed into the surrounding environment by people who are infected, particularly in shed skin particles and in debris from monkeypox skin lesions and scabs. The virus is relatively hardy and under appropriate conditions can remain infectious on surfaces for weeks, creating a potential infection risk to others.
The UK Health Security Agency (UKHSA) recommends that patients with monkeypox who have severe disease requiring hospital admission are cared for in isolation rooms, with infection prevention and control (IPC) precautions that aim to contain potentially infectious virus within the room and protect staff who enter. However, to date it has been unclear whether these measures are proportionate to the potential virus exposure risks.
To investigate this, researchers from the Liverpool School of Tropical Medicine, the University of Oxford's Nuffield Department of Medicine and the UKHSA conducted a study which collected samples from the rooms of patients hospitalized with monkeypox. The findings have been published in The Lancet Microbe.
The research team assessed the extent of virus shedding onto surfaces in specialist isolation rooms containing patients admitted to hospital for the management of severe monkeypox. They also investigated whether the virus was detectable in air samples from the rooms.
The researchers found that viral DNA shed by the patients could be found on multiple surfaces throughout the isolation rooms (56 (93%) positive by PCR out of 60 samples). Monkeypox virus DNA was also found on personal protective equipment (PPE) worn by healthcare workers caring for these patients, and in the anterooms where they remove their PPE. Monkeypox virus DNA was also detected in five out of twenty air samples taken within these isolation rooms.
Changing bed linen was an activity particularly associated with detection of monkeypox virus DNA in air samples in the room. This suggests that viral particles, probably in shed skin particles, can become suspended in the air when bed sheets are changed. Monkeypox virus capable of replicating in cells under laboratory conditions (an indicator that the virus could infect other people) was identified in two of four PCR-positive samples selected for virus isolation. This includes air samples collected during the bed linen change.
https://medicalxpress.com/news/2022-10-monkeypox-virus-widely-specialist-hospital.html
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Ebola:
Uganda to test 2 Ebola vaccines during current outbreak
The Uganda Ministry of Health announced that it will try two vaccines against the Sudan Ebola strain currently causing cases in that country.
The vaccines include one developed at the University of Oxford in the United Kingdom, and the other manufactured by Sabin in the United States.
According to the latest report from the World Health Organization (WHO) on the current outbreak in Uganda, there have been 20 suspected cases, all fatal. Between Sep 19 and Oct 9, 68 cases of the virus were detected, including the 20 suspected cases and 48 lab-confirmed cases.
"Thirty-seven fatalities have been registered including 17 confirmed cases, for an overall case fatality ratio of 54.4%, and 35.4% among confirmed cases," the WHO said.
The WHO said cases seem to be declining, though deaths are increasing. Authorities have also begun testing bats in the outbreak regions, and so far, four species have been identified and 52 samples taken.
Finally, according to Ugandan news media, Uganda's president has told traditional healers and herbalists not to treat people with suspected Ebola; he also directed security officials to arrest people with suspected infections who refuse to isolate.
Oct 13 The Observer story
Oct 13 WHO weekly bulletin
Oct 13 The Star story
https://www.cidrap.umn.edu/news-perspective/2022/10/news-scan-oct-13-2022
Note:
About 140 travelers from Uganda arrive in the U.S. daily. These passengers are now funneled into five U.S. airports for SUDV screening. These travelers are followed-up post arrival by the U.S. government.
However, since SUDV infection incubation periods can reach seven days, airport screening may miss infected passengers, said the CDC team.
In the U.S., the CDC has mobilized various resources, such as multi-disciplinary CDC Ebola Response Teams and coordinating with the 10 Regional Special Pathogens Treatment Centers. Currently, nine laboratories can test SUDV samples.
https://www.precisionvaccinations.com/us-prepares-sudan-ebolavirus-potential-arrival
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Influenza:
https://twitter.com/michaelzlin/status/1578659654086770688?s=20&t=tbUGqzSwyJDmBgrtr6oBtw
Diagnostics:
Monkeypox: FDA authorizes Abbott test
The Food and Drug Administration has issued an emergency use authorization for Abbott's monkeypox test, which will offer real-time polymerase chain reaction (PCR) test results for clinicians. The test relies on swabs of lesions. This is the first commercial test to be authorized for monkeypox detection.
Drugs and Vaccines:
Exciting day for kids ages 5-11 who are now eligible for the updated COVID booster. #CallYourPediatrician to schedule your child's booster and ask about getting their flu shot at the same time! https://t.co/dbFrNIbOmf
— American Academy of Pediatrics (@AmerAcadPeds) October 12, 2022
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Boosters save lives vs Omicron, from the largest US healthcare system @VeteransHealth with ~490,000 matched individuals, across all ages 18+https://t.co/UHh4iSdX8p
— Eric Topol (@EricTopol) October 10, 2022
new @AnnalsofIM by @gnioannou and colleagues pic.twitter.com/M0S9TOLJJO
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Pfizer and its partner BioNTech reported its updated booster generated a strong immune response against the currently circulating BA.5 and the BA.4 subvariants of Omicron.
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Antiviral molnupiravir purchased by UK government does not lower risk of hospital admission, trial shows
BMJ 2022; 379 doi: https://doi.org/10.1136/bmj.o2441 (Published 11 October 2022)
Molnupiravir, a covid-19 antiviral drug bought by the UK government in the amount of 2.23 million doses, is no better than placebo at lowering the risks of death and hospital admission, a pivotal UK trial has found.
Preliminary results released from the Panoramic trial of 25 783 people who were randomly assigned to open label treatment with molnupiravir plus usual care or to usual care alone found no significant difference between the two groups for the primary endpoint of death or hospital admission.1 The study has been published as a preprint and has not yet been peer reviewed.
The UK was the first country to authorise Merck Sharp and Dohme’s molnupiravir (Lagevrio) for the treatment of mild to moderate covid-19 in adults with at least one risk factor for severe illness, in November 2021.2 The European Medicines Agency has still not approved the drug.
https://www.bmj.com/content/379/bmj.o2441
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#Vaccination cut #LongCOVID risk for #rheumatology patients. Patients with rheumatologic conditions who developed breakthrough #COVID19 #infection AFTER #vaccination were LESS LIKELY to suffer long-term symptoms than unvaccinated similar patients https://t.co/iWofuWGKWl pic.twitter.com/DBGXR4rEGM
— Dr. Melvin Sanicas (@Vaccinologist) October 12, 2022
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A drug developed at #NIH-funded @scrippsresearch has been shown to block #COVID19 infection in animals. By preventing the ACE2 molecule from binding to the SARS-CoV-2 spike protein, the drug stops viral entry & infection. https://t.co/HLqVfxrBsl
— Lawrence A. Tabak (@NIHDirector) October 14, 2022
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Now do you see?https://t.co/xTtBmkImjK
— Joe Oliver (@joeolivermd) October 12, 2022
h/t @MoriartyLab @Billius27 @lisa_iannattone pic.twitter.com/HrA6iIaCgu
Devices:
On a related front, the largest randomized trial of daily rapid antigen tests (~55,000 participants) for guiding length of isolation after exposure (vs 10 days) showed reduced attack rates (spread) 6.3 vs 7.5%, respectivelyhttps://t.co/MZFqfmoj7t @isaperena @UKHSA pic.twitter.com/2BEDCCJVY1
— Eric Topol (@EricTopol) October 11, 2022
Epidemiology/Infection control:
That is a gigantic gap pic.twitter.com/A1PhBSNYkQ
— Justin Feldman (@jfeldman_epi) October 14, 2022
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14% of Americans have Long Covid – and that’s a conservative count. 4 out of 5 of them have symptoms that impact their daily activities. People can’t work or take care of their families. We need to put the pedal to the metal on researching treatment. https://t.co/VguhHnj5L0
— Zeke Emanuel (@ZekeEmanuel) October 7, 2022
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Most likely to support continued mask wearing: Black people, and people making <$40K / year. Black ppl also more likely to know someone who died of Covid, and to have had finances adversely impacted by it. pic.twitter.com/ODQ2BrpMfA
— Katie Bach (@kathrynsbach) October 14, 2022
both from this excellent Covid resource: https://www.kff.org/coronavirus-covid-19/dashboard/kff-covid-19-vaccine-monitor-dashboard/
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Dear God. This is the single best piece on schools and #COVID19 that I've read in two+ years. Thank you @KeeangaYamahtta for your brilliance and laser-like ability to get to the heart of the matter. https://t.co/dS2KGgPfvu
— Gregg Gonsalves (@gregggonsalves) October 13, 2022
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https://twitter.com/DataDrivenMD/status/1579128777690742789?s=20&t=tbUGqzSwyJDmBgrtr6oBtw
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Please note that even the COVID transmission map is losing reliability because we are under-testing, states are reporting tests less frequently, and we are not counting rapid tests.@IHME_UW estimates that only 4-5% of all infections are being reported! https://t.co/CQxs3e2h0P pic.twitter.com/3ATDUpTPaX
— Dr. Lucky Tran (@luckytran) October 11, 2022
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The Oktoberfest in Munich acted as a massive super spreading event, which is hitting the city extremely hard, and it's feared to be getting worse
— Dr Elisa Perego (@elisaperego78) October 11, 2022
Monkeypox:
https://twitter.com/MackayIM/status/1581069112201334786?s=20&t=jqulX57vMjaIRvrWTf7BpQ
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Influenza:
As of 01oct2022 (thats a week ago)
— JusDayDa (@JusDayDa) October 8, 2022
Georgia and DC hardest, Texas as well
Outpatient Respiratory Illness Visits in 2022 are significantly higher than this week in 2021
Outpatient Respiratory visits are more than double a traditional year (not good)
Consider discussing flu vax pic.twitter.com/afhi1ZHypY
Tips, general reading for public:
Ventilate.
Mask.
Vax.
Politics:
Covid:
From outside the US, across the pond, data scientist @jburnmurdoch @FThttps://t.co/XVxfx5dESw
— Eric Topol (@EricTopol) October 15, 2022
"Over the past 18 months, the politicisation of science may have directly cost as many as 60,000 American lives" pic.twitter.com/lMFjwJlFXG
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COVID19 Treatment saves lives
— Michael Mina (@michaelmina_lab) October 7, 2022
Nevertheless, a stunning plot of Paxlovid use based on population voting behavior
Paxlovid treatment is prescribed for COVID much more frequently in populations that primarily voted for Biden vs Trump
Even now, awareness is low in some populations pic.twitter.com/PzutnjBaOj
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It’s telling that aerosol scientists wear high quality masks at their conferences, even when presenting on panels and during photo ops.
— Eric Kennedy (@ericbkennedy) October 7, 2022
As the tongue-in-cheek says, “if the bomb squad tech is running, try to keep up.” And, if the aerosol experts are masked, maybe we should too. https://t.co/29GoVSEboE
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Meanwhile, the long term care industry is lobbying against occupational health regulation for airborne viruses https://t.co/4L53tSUnKS
— Justin Feldman (@jfeldman_epi) October 9, 2022
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https://twitter.com/CPita3/status/1574177983346184198?s=20&t=tbUGqzSwyJDmBgrtr6oBtw
Elections:
New definition of inflation: What happens when corporations raise prices during times of unprecedented profits in order to damage a current POTUS who wants them to pay taxes.
— Juli Bunting#BlackLivesMatter (@JuliBunting) October 14, 2022
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"We're gonna fix the whole country."
— Michael Beschloss (@BeschlossDC) October 9, 2022
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What was that thing where the DOJ didn’t want to charge Trump before the midterms because they don’t want to be seen as meddling in elections? https://t.co/0UGdqYFHKS
— Julia Ioffe (@juliaioffe) October 6, 2022
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A court-ordered Black district got carved into powerless bits: great reporting:
— Jane Mayer (@JaneMayerNYer) October 11, 2022
How DeSantis Remade Florida's Congressional Districts — ProPublica https://t.co/goRG8AvNfI
GOP/misc:
Two republican senators have introduced legislation to eliminate Medicare's new authority to negotiate Rx prices. This is what you have to look forward to if voters give republicans control of the Senate.
— counselorRick (@CapriolaRichard) October 10, 2022
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Putting aside how characteristically gross it is that Fox would relish in a family’s struggles with addiction for political gain, this is also a beautiful tutorial in how a loving father should reach out to his son in the throes of substance use disorder. pic.twitter.com/LP56WvOjKu
— Pat Cunnane (@PatCunnane) October 11, 2022
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BREAKING: The White House says Social Security payments are expected to be up to $140 HIGHER per month, on average, starting in January. The GOP meanwhile, wants to CUT social security. Remember in November!
— CALL TO ACTIVISM (@CalltoActivism) October 12, 2022
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Common tactic:
Everyone retweet this and expose @EliseStefanik for the fraud she is. She’s bragging about money from a bill she voted against. The GOP doesn’t care about people. They care about power. And they know people love Biden’s bill. Share far and wide!! https://t.co/B6LZX0z5jI pic.twitter.com/Tsh42E22pL
— Mueller, She Wrote (@MuellerSheWrote) October 14, 2022
Who knew there were so many socialist Republicans in Congress. pic.twitter.com/DQaZELKvJq
— President Biden (@POTUS) October 14, 2022
TFG/Jan 6:
My friend and I are taking a field trip to court! ☺️ pic.twitter.com/atkIADB1NF
— Mrs. F (@ms_frazzled) October 14, 2022
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BREAKING: Trump PERSONALLY told staff to move the documents — from a storage room at Mar-a-Lago, to his residence at the compound, after the feds asked for the docs. Per one of the staffers and corroborated by security footage.
— Tristan Snell (@TristanSnell) October 13, 2022
Hard evidence Trump intentionally hid the docs.
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https://twitter.com/duty2warn/status/1580624129912602624?s=20&t=tbUGqzSwyJDmBgrtr6oBtw
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Pelosi’s response to hearing Trump might march to the Capitol is definitely worth watching pic.twitter.com/wpUlvKoqwT
— Acyn (@Acyn) October 14, 2022
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Guns:
An Indiana 5th grade teacher was arrested for having a “kill list” of students and colleagues, saying: “I’m having trouble with my mental health, and sometimes the kids don’t listen...”
— Shannon Watts (@shannonrwatts) October 15, 2022
Indiana law allows teachers to be armed without training. #inlegis https://t.co/JSsGweoj75
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Oz is a complete fraud who once who once endorsed red flag laws and called for an end to the ban on CDC funding for gun violence research, but now says he supports gun violence against members of an “overly intrusive government.”
— Shannon Watts (@shannonrwatts) October 14, 2022
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Thread about violence against women:
https://twitter.com/MaryKoCo/status/1578901970177642496?s=20&t=tbUGqzSwyJDmBgrtr6oBtw
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Reproductive health/Abortion:
Contraception.
— Edge (@czarbucks) October 9, 2022
CONTRACEPTION!!
Are they f*ing kidding us? https://t.co/09kndwX2Fg
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This will blow your mind. New Hampshire’s Republican Senate candidate Don Bolduc says abortion decisions “belong” to Republican “gentlemen” state representatives, and that “as a man”, women “get the best voice” when men decide how to regulate their rights. pic.twitter.com/zv4twOWdoU
— Mike Sington (@MikeSington) October 9, 2022
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Mississippi promoting tax breaks for #antiabortion corporate donations. What's next?https://t.co/atzPPDxFg3
— Judy Stone (@DrJudyStone) October 11, 2022
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The impact this will have on the health of women can not be overstated. Contraception, IVF, and even normal pregnancy care will be at risk as doctors must navigate a complex world of felony charges related to potential embryos. 2/5
— Rep. Beth Liston (@Liston4Ohio) October 6, 2022
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Ohio's abortion ban is preventing cancer patients from receiving life-saving treatment. Devastating piece from @shefalil. https://t.co/bxOY0zttyo pic.twitter.com/AMjpS5rPHs
— Mark Joseph Stern (@mjs_DC) October 7, 2022
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Three Jewish moms are suing the AG over KY's abortion ban, arguing it gives preference to Christian beliefs and diminishes Jews' religious freedoms. “In Judaism, reproductive health of a mother is between the mother, her rabbi and her doctor-- not the AG."https://t.co/moiFknArtr
— Brian Tyler Cohen (@briantylercohen) October 6, 2022
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BIG NEWS:
— Congresswoman Kathy Manning (@RepKManning) October 11, 2022
Following my calls on Walmart to rescind their harmful policy of denying the women of North Carolina miscarriage medication based on perceived pregnancy status, Walmart rescinded this harmful policy & will resume dispensing misoprostol without unnecessary restrictions.
Antisemitism:
https://twitter.com/leahmcelrath/status/1579129970672439297?s=20&t=tbUGqzSwyJDmBgrtr6oBtw
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As someone who often receives antisemitic attacks online, I appreciate all the allies speaking out. American Jews are merely 2% of the US population but are victims of 60% of religious hate crimes. We must stay vigilant, esp as @gop members are spewing Great Replacement Theory
— Sari Beth Rosenberg (@saribethrose) October 10, 2022
Book bans:
Barnes & Noble’s Banned Books section (kids edition). Please zoom in on the reasons, and question why we would ever allow to these small minded people decide what our children can read.
— PoliticsGirl (@IAmPoliticsGirl) October 8, 2022
*Photo credit: Brian Gallagher pic.twitter.com/u32RXpMpcH
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Climate:
"Earth’s wildlife populations have plunged by an average of 69% in just under 50 years, according to a leading scientific assessment, as humans continue to clear forests, consume beyond the limits of the planet and pollute on an industrial scale."https://t.co/eJCmrhitRb
— Greta Thunberg (@GretaThunberg) October 13, 2022
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Greed:
Thread about denials of medical care by insurers--the most ordinary possible story about healthcare:
SCENE: After a couple ER visits and a hospitalization, the doctor's office began a prior authorization request to get the drug right after Labor Day. The insurance responded by denying. Normal. The pharma company, after a couple weeks, gave us some free "bridge" drug.
— carolyn johnson (@Carolynyjohnson) October 12, 2022
LGBTQ:
An absolute masterclass by Jon Stewart. https://t.co/6B1kzmsRhn
— Brian Tyler Cohen (@briantylercohen) October 7, 2022
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Racism/Georgia:
Police at Hartsfield-Jackson have been stopping passengers boarding planes demanding to search their luggage, and seizing - and keeping - cash. They call these stops - which overwhelmingly target people of color - "consensual encounters." https://t.co/IiSZ8usvqi
— inverted vibe curve: burgertown must be defended (@PatBlanchfield) October 12, 2022
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Medicare:
If you can't access the article, here's a gift link: https://t.co/IyInkBgtUm
— Harry Thomas (@DrHarryThomas) October 8, 2022
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Voter registration:
“No one has asked me that before” How patients are learning that their physical health and civic health are inextricably linked. @AlisterFMartin @MGHMedicine https://t.co/CQNGF1iCDr via @BostonGlobe
— Kay Lazar (@GlobeKayLazar) October 14, 2022
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Arizona:
https://t.co/IAepDY42JW Arizona Gov. Doug Ducey has some explaining to do!
— Elli Anderson VoteBlue (@ElliLAnderson) October 10, 2022
Florida:
Great takedown of Ladapo:
Florida just announced the results of an analysis that they performed, saying the results show "an increased risk of cardiac-related death among men 18-39" for the mRNA vaccines, and recommend this group not receive these vaccines.
— Kristen Panthagani, MD, PhD (@kmpanthagani) October 9, 2022
Is this justified? Let's look at the data... pic.twitter.com/hfHrg6CMNb
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And the source of the funds is interest on COVID-19 relief funds.
— Daniel Uhlfelder (@DWUhlfelderLaw) October 10, 2022
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Georgia:
Oh shit lol pic.twitter.com/ArJC1510TQ
— Acyn (@Acyn) October 14, 2022
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"I'm all for cutting insulin, but first of all, you gotta eat right. If you don't eat right, insulin won't do anything for you. You need to reduce gas prices so they can afford insulin." - Walker
— Bärí A. Williams, Esq. (@BariAWilliams) October 14, 2022
WHAT?! #GASenDebate
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Nevada:
More: https://t.co/OMNJajmy7t
— Adam Parkhomenko (@AdamParkhomenko) October 12, 2022
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Pennsylvania:
Matt Gaetz' in-laws hosted a high-dollar fundraiser for Dr. Oz at a museum last night in which Oz stood in front of one of Hitler's cars, which showed up in the social media photos. Also, incel king Jordan Peterson joined by Zoom.
— Laura Bassett (@LEBassett) October 7, 2022
Campaign going great https://t.co/GZNb3s2hn8
~ ~ ~
All you need to know about our media is that Fetterman’s legitimate medical situation is receiving breathless and irresponsible round-the-clock coverage and Herschel Walker’s request for “visual aids” so he could understand debate questions was barely a blip on the radar.
— Jared Yates Sexton (@JYSexton) October 12, 2022
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Mastriano distances from Gab CEO, doesn't disavow anti-Jewish commentshttps://t.co/Ov9KsxsZFx
— Max Burns (@themaxburns) October 12, 2022
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Texas:
https://twitter.com/RexChapman/status/1580594164726919168?s=20&t=tbUGqzSwyJDmBgrtr6oBtw
Saudi Arabia:
NEWS—Senate Foreign Relations Chair Menendez is about to call for an immediate freeze of U.S. cooperation w/ Saudi Arabia.
— Andrew Desiderio (@AndrewDesiderio) October 10, 2022
Menendez has veto power over foreign weapons sales.
“I will not green light any cooperation w/Riyadh until the Kingdom reassesses its position” on Ukraine.
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Ukraine:
elon musk told me he had spoken with putin and the kremlin directly about ukraine. he also told me what the kremlin’s red lines were.
— ian bremmer (@ianbremmer) October 11, 2022
~ ~ ~
Musk threatens to stop funding Starlink internet Ukraine relies on in war https://t.co/3Qh9FKRGTv
— Judy Stone (@DrJudyStone) October 14, 2022
Feel good du jour:
Remember, there’s infrastructure, and then there’s Dutch infrastructure. pic.twitter.com/19yLueJjDs
— Brent Toderian (@BrentToderian) October 14, 2022
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Butterfly
— Gabriele Corno (@Gabriele_Corno) October 7, 2022
by Johannes Stötter pic.twitter.com/jv2YFPUJ7m
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Good News Alert:
— Goodable (@Goodable) October 9, 2022
Dolly Parton is partnering with state of California to provide all children in the state under the age of five with a free book every month.
The bill, partnering with Dolly's Imagination Library, received bipartisan support and will go into effect next year. pic.twitter.com/kx1WEHh6DL
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Frozen moments art... pic.twitter.com/CSL1FCP76q
— Figen... (@TheFigen_) October 6, 2022
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A hug makes you feel good all day pic.twitter.com/769lc2D1x5
— Gabriele Corno (@Gabriele_Corno) October 8, 2022
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Baby hedgehogs are known as hoglets. Photo: Ann and Steve Toon pic.twitter.com/yGCFBhyrJf
— Fascinating (@fasc1nate) October 10, 2022
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These kids ride a ‘bike bus’ to school. Residents line the streets and cheer. https://t.co/ev58YDsqdu
— Judy Stone (@DrJudyStone) October 13, 2022
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My favorite fact about Angela Lansbury is that during her MURDER SHE WROTE era she made it a practice to hire guest actors of the golden age that had aged out of the game because it allowed them to earn the union points they needed for insurance, pensions, etc.
— Tess Sharpe (@sharpegirl) October 11, 2022
Comic relief:
Dog's Reaction when he hears his Favourite Artist and Song.
— B&S (@____B_S____) October 9, 2022
by sarveshak99 pic.twitter.com/nUsxhL2alz
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Obi-Wan Cannoli pic.twitter.com/l4BwjntX2O
— Marshall Julius (@MarshallJulius) October 9, 2022
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he's got a crush pic.twitter.com/z1ic4hoemd
— cats being weird little guys (@weirdlilguys) October 9, 2022
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One of the greatest moments on Parkinson came 40yrs ago in 1982 when BUDDY RICH and ROY CASTLE improvised the hell out of it in order to buy time for a (late running) surprise special guest - SAMMY DAVIS JR.
— Michael Warburton (@MichaelWarbur17) October 9, 2022
pic.twitter.com/cJDfV8nBnk
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https://twitter.com/Yoda4ever/status/1579131571856183297?s=20&t=tbUGqzSwyJDmBgrtr6oBtw
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this games rigged pic.twitter.com/dqBy9lOTzx
— Dont Show Your Cat (@DontShowYourCat) October 7, 2022
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When you realise they lied about going to the opera just to get you to the vet. pic.twitter.com/QOLNxXxS6V
— Paul Bronks (@SlenderSherbet) October 7, 2022
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https://twitter.com/thepuppiesclub/status/1580576593881092096?s=20&t=tbUGqzSwyJDmBgrtr6oBtw
Perspective/Poem
William Shatner on his Blue Origin flight to space: "It was among the strongest feelings of grief I have ever encountered." https://t.co/CI1WDV17oe pic.twitter.com/z0jyFRzJ7w
— graham starr (@GrahamStarr) October 9, 2022
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Spilling truth... Sad but true... pic.twitter.com/9hu9nF3T4y
— Figen... (@TheFigen_) October 13, 2022
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https://twitter.com/arealmofwonder/status/1579498322716676096?s=20&t=tbUGqzSwyJDmBgrtr6oBtw
Bits of beauty:

